Increased mGluR5 signaling underlies OCD-like behavioral and striatal circuit abnormalities in mice

2016
Written By Stellate Comms

Ade KK, Wan Y, Hamann HC, O’Hare JK, Guo W, Quian A, Kumar S, Rodriguez R, Wetsel WC, Conn PJ, Dzirasa K, Huber KM, Calakos N (2016) Biological Psychiatry

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Rat intersubjective decisions are encoded by frequency-specific oscillatory contexts
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Dysregulation of prefrontal cortex-mediated slow evolving limbic dynamics drives stress-induced emotional pathology